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KMID : 1143420180110220698
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Public Health Weekly Report
2018 Volume.11 No. 22 p.698 ~ p.706
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Epidemiological characteristics of patients with severe fever with thrombocytopenia syndrome in Republic of Korea in 2017
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Seo Choong-Won
Kim Jeong-Hyun
Kim Eun-Young
Lee Seung-Eun
Park Hye-Kyung
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Abstract
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Background: The nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) was initiated in 2013
in the Republic of Korea. SFTS is an emerging tick-borne disease characterized by fever, thrombocytopenia and
gastrointestinal symptoms including diarrhea, abdominal pain and vomiting. We analyzed the epidemiological and clinical
features of reported SFTS cases in 2017.
Methods/Results: A total of 272 cases were analyzed: 270 were laboratory-confirmed cases and 2 were suspect cases.
There were 54 deaths (Case Fatality Rate, CFR: 19.9%) and the majority of cases were reported from May to November. The peak of cases were observed in October with 79. The age distribution of cases ranged between 19 and 91 years (median 66 years). 253 (93.0%) cases were aged more than 50 years and 118 (43.4%) cases were farm workers. Geographically, cases were mainly reported in Gyeonggi, Gangwon, Gyeongbuk, Chungnam, and Jeju provinces. In terms of risk behaviors, 197 cases (72.4%) had history of outdoor activities including farmworks.
Conclusion: Age and neurologic symptoms including decreased level of consciousness, slurred speech and convulsions
were markedly associated with SFTS-related mortality. The risk of death was 6.931 (95% CI=2.217-22.579) times higher
among the cases with neurological symptoms than among the cases without ones. Those who experience symptoms after outdoor activities such as fever, gastrointestinal symptoms are advised to receive early diagnosis and proper treatment.
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KEYWORD
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Severe fever with thrombocytopenia syndrome, Farm workers, Thrombocytopenia, Fever, Gastrointestinal symptoms
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